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Genomics in H&N Cancer

B064

TRAF2 ASSOCIATED WITH FAK IS ESSENTIAL FOR HEAD AND NECK METASTASIS

Genomics in H&N Cancer

Sabrina Daniela Silva Wurzba1, Bin Xu1, Fabio Marchi2, Krikor Bijian1, Alex Mlynarek1, Michael Hier1, Luiz Paulo Kowalski2, Moulay A. Alaoui-Jamali1

1McGill, 2AC Camargo


B065

THE SCREENING AND IDENTIFICATION OF MOLECULES RELATED TO NASOPHARYNGEAL CARCINOMA RADIORESISTANCE

Genomics in H&N Cancer

Yuanzheng Qiu, Ph, D, Yong Liu, PhD, Guo Li, PhD, Shuling Ren, Chao Liu, Donghai Huang, PhD

Department of Otolaryngology and head-neck surgery, Xiangya Hospital, Central South University


B066

TRAF3/CYLD MUTATIONS DEFINE A DISTINCT SUBSET OF HPV-ASSOCIATED HEAD AND NECK SQUAMOUS CELL CARCINOMA

Genomics in H&N Cancer

Andrew B Sewell, MD, Michael Hajek, MSc, Susan Kaech, PhD, Barbara Burtness, MD, Wendell G Yarbrough, MD, MMHC, Natalia Issaeva, PhD

Yale University


B067

IMMUNOHISTOCHEMICAL EVALUATION OF NOTCH PATHWAY ACTIVATION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Genomics in H&N Cancer

Eleni M Rettig, MD1, Justin A Bishop, MD1, Nishant Agrawal, MD2, Rajni Sharma, PhD1, Ryan J Li, MD3, Theresa Guo, MD1, Wayne Koch, MD1, Joseph A Califano, MD4, Christine H Chung, MD5, Carole Fakhry, MD, MPH1

1Johns Hopkins, 2University of Chicago, 3Oregon Health & Science University, 4University of California San Diego, 5Moffitt Cancer Center & Research Institution


B068

DETECTION OF METHYLATED TUMOR DNA IN PLASMA AND SALIVA AFTER TREATMENT PREDICTS RECURRENCE IN HPV-NEGATIVE HEAD AND NECK SQUAMOUS CELL CARCINOMA

Genomics in H&N Cancer

Sunny Haft, MD1, Theresa Guo, MD2, Minya Pu1, John Pang, MD1, Jing Zhang1, Zubair Khan, MBBS2, Darya Gaykalova, PhD2, Joseph Califano, MD1

1University of California San Diego, 2Johns Hopkins


B069

HIGH ACCURACY TO DISTINGUISH MALIGNANT FROM NON-MALIGNANT THYROID TISSUES USING DNA METHYLATION PROFILING

Genomics in H&N Cancer

Mateus Barros Filho, PhD1, Mariana dos Reis, PhD2, Caroline Beltrami, MSc1, Fabio Marchi, PhD1, Hellen Kuasne, PhD1, Antonio C Pinto, MD, PhD1, Srikant Ambatipudi, PhD3, Zdenko Herceg, PhD3, Luiz P Kowalski, MD, PhD1, Silvia R Rogatto, PhD2

1AC CAmargo Cancer Center, 2Vejle Hospital and University of Southern Denmark, 3International Agency for Research on Cancer


B070

TARGETING MECHANISMS OF RESISTANCE TO APOPTOSIS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Genomics in H&N Cancer

Cory Fulcher1, Carlos Thomas1, Richard V Smith, MD2, Thomas J Belbin, PhD1, Thomas Harris, PhD1, Geoffrey Childs, PhD1, Missak Haigentz, MD2, Madhur Garg, MD2, Rafi Kabaritti, MD2, Bradley A Schiff, MD2, Michael B Prystowsky, MD, PhD1, Nicolas F Schlecht, PhD1, Gregory Rosenblatt, PhD1, Chandan Guha, MB, BS, PhD1, Evripidis Gavathiotis1, Thomas J Ow, MD, MS2

1Albert Einstein College of Medicine, 2Montefiore Medical Center


B072

DIFFERENTIAL GENE EXPRESSION ANALYSIS OF INVASIVE AND NON-INVASIVE FOLLICULAR VARIANT OF PAPILLARY THYROID CARCINOMA

Genomics in H&N Cancer

Christopher Pool, MD, David Goldenberg, MD, FACS, Erik Washburn, MD, Joshua Warrick

Penn State Hershey Medical Center


B073

DEVELOPMENT AND CHARACTERIZATION OF AN IN VITRO MODEL FOR RADIATION INDUCED FIBROSIS

Genomics in H&N Cancer

Dhruv Kumar, PhD1, Jacob New1, Sreeya Yalamanchali, MD1, Sean Parsel, MD1, Natalie New1, Sumedha Gunewardena2, Ossama Tawfik, MD3, Chris Lominska, MD4, Bruce Kimler, PhD4, Kiran Kakarala, MD1, Terrence Tsue, MD1, Yelizaveta Shnayder, MD1, Kevin Sykes, PhD1, Subhash Padhye, PhD5, Sufi M Thomas, PhD1

1University of Kansas Department of Otolaryngology, 2University of Kansas Department of Molecular and Integrative Physiology, 3University of Kansas Department of Pathology and Laboratory Medicine, 4University of Kansas Department of Radiation Oncology, 5University of Pune Department of Chemistry


B074

MUTATION PROFILING OF OLFACTORY NEUROBLASTOMA, ESTABLISHMENT OF NOVEL OLFACTORY NEUROBLASTOMA CELL LINE MODELS AND RESULTS FROM DRUG SCREENING

Genomics in H&N Cancer

Matt Lechner, MD, PhD1, Graham Wells2, Chris Steele, PhD3, Nischalan Pillay3, Tim Fenton, PhD3, Chris Kranjec, PhD4, Luke Williams, MBBS3, Debbie Ho3, Nur Ayne Zaharoff3, Martin Forster, PhD1, Amrita Jay, MBBS1, Wendell G Yarbrough, MD5, Volker Schartinger, MD6, Nils Engel7, Ulrich Schueller, MD7, David Capper, MD8, Udo Oppermann, PhD2, David Howard, MD1, Valerie J Lund, MD, CBE1

1University College London Hospitals, 2University of Oxford, 3University College London, 4University of Cambridge, 5Yale School of Medicine, 6University Hospital of Innsbruck, 7University Hospital Hamburg-Eppendorf, 8Ruprecht-Karls University Heidelberg