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Systemic Therapy / Immunotherapy

AHNS-016

CUMULATIVE SUPPRESSIVE INDEX AS A PREDICTOR OF RELAPSE FREE SURVIVAL AND OVERALL SURVIVAL IN HPV- ORAL SQUAMOUS CELL CARCINOMAS WITH NEGATIVE RESECTION MARGINS

Systemic Therapy / Immunotherapy

Lauren N Hum, MD, DMD1, Daniel Bethmann, MD2, Zipei Feng, MD, PhD3, Shu-Ching Chang, PhD4, Alexander Eckert, MD5, Claudia Wickenhauser, MD2, Bernard A Fox, PhD6, R. Bryan Bell, MD, DDS, FACS7

1Department of Oral and Maxillofacial Surgery, Oregon Health and Science University, Portland, OR, 2Institute of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany, 3Bobby R. Alford Department of Otolaryngology, Baylor College of Medicine, Baylor, TX, 4Medical Data Research Center, Providence St. Joseph's Health, Portland, OR, 5Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany, 6Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Portland, OR, 7Providence Oral, Head and Neck Cancer Program and Clinic, Portland, OR


AHNS-068

COMBINED INHIBITION OF WEE1 AND RAD51 ENHANCES CELL KILLING IN HNSCC

Systemic Therapy / Immunotherapy

Antje Lindemann, Ameeta A Patel, Hideaki Takahashi, Lin Tang, Abdullah A Osman, Jeffrey N Myers

The University of Texas MD Anderson Cancer Center


AHNS-069

ROLE OF INDUCTION CHEMOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA

Systemic Therapy / Immunotherapy

Ahmed S Abdelmeguid, MD, PhD1, Natalie L Silver, MD, PhD2, Mongkol Boonsripitayanon, MD1, Renata Ferrarotto, MD1, Ann M Gillenwater1, Ehab Y Hanna, MD1

1University of Texas MD Anderson Cancer Center, 2University of Florida College of Medicine


AHNS-070

SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF NF-KB MEDIATED APOPTOSIS OF THE ANTI-INFLAMMATORY BOTANICAL DRUG APG-157 IN PATIENTS WITH ORAL SQUAMOUS CELL CARCINOMA

Systemic Therapy / Immunotherapy

Saroj Basak, PhD1, Marco Morselli, PhD1, Alakesh Bera, PhD2, Alexander Yoon, BS1, Meera Srivastava, PhD2, Kym F Faull, PhD1, Matteo Pellegrini, PhD1, Chan Jeong, BS1, Eri Srivatsan, PhD3, Marilene B Wang1

1UCLA, 2Uniformed Services University of Health Sciences, 3VA Greater Los Angeles Healthcare System


AHNS-072

ASSOCIATION OF NEUTROPHIL-TO-LYMPHOCYTE RATIO DYNAMICS AND OUTCOMES WITH IMMUNE CHECKPOINT INHIBITION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Systemic Therapy / Immunotherapy

Marcus A Couey, MD, DDS1, Mark T Schmidt, BSc1, Allen C Cheng, MD, DDS2, Ashish A Patel, MD, DDS2, R. Bryan Bell, MD, DDS1, Tanguy Y Seiwert, MD3, Rom S Leidner, MD1

1Earle A. Chiles Research Institute at Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 2Head and Neck Institute, Portland, OR, 3Department of Medicine, Section of Hematology/Oncology, The University of Chicago Medicine, Chicago, IL


AHNS-074

THE IMPACT OF NEOADJUVANT PRE-SURGICAL PD-1 INHIBITION ON THE IMMUNE PHENOTYPE IN PATIENTS WITH ORAL CAVITY CANCER.

Systemic Therapy / Immunotherapy

David M Neskey, MD, MSCR1, John Kaczmar, MD1, Hannah Knochelman, BS1, Megan Wyatt, BS1, Ying Xiong, PhD1, Michael Froehlich, BS1, Anvesh Kompelli, BS2, M. Rita Young, PhD1, Chrystal Paulos, PhD1

1Medical University of South Carolina, 2Louisiana State University ShreveportLouisiana State University Health - Shreveport School of Medicine