JAMA Otol Logo Orlando 2013 AHNS Meeting Location
American Head & Neck Society
Annual Meeting, April 10-11, 2013
JW Marriott Grande Lakes
Orlando, Florida

During the
Combined Otolaryngology Spring Meeting
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Presentation: P049
Topic: Clinical - Gen. Head & Neck Surgery
Type: Poster
Date: Wednesday - Thursday, April 10 - 11, 2013
Session: Designated Poster viewing times
Authors: Timothy S Wong, FRACDS, OMS, Colin Liew, MD, Nicholas Kalavrezos, Mr, Amrita Jay, Bagrat Lalabekyan, MD, Timothy Beale, MD, Simon Morley, MD, Phillip Pirgoussis, FRACDS, OMS
Institution(s): University College London Hospital

For over a century, ionising radiation has been known to induce malignancies in almost every organ, the most common being leukaemias and sarcomas. Radiation-induced sarcomas of the head and neck are rare tumours which present multiple resective and reconstructive challenges to the head and neck surgeon. We present our 12 year single-institution series of 17 radiation-induced sarcomas of the head and neck and compare their behaviour and outcomes to our series of 130 non-radiation induced head and neck sarcomas.

Aim: To compare the clinical, radiologic, pathologic characteristics and treatment outcomes of our series of 17 radiation-induced sarcomas of the head and neck with our cohort of 130 non-radiation induced head and neck sarcomas

Method: We performed a retrospective study from the University College London Hospital Head and Neck Sarcoma Database of our 17 radiation-induced head and neck sarcomas over 2000-2012 including demographics, radiation characteristics, clinical and radiologic presentation, resective and reconstructive experience and treatment outcomes

Results & Conclusions: Our series of radiation-induced head and neck sarcomas all had radiation doses of >40Gy, a variable latency period and almost universally were high-grade sarcomas.  Our treatment protocol consisted of neo-adjuvant chemotherapy and aggressive surgical resection with our series of radiation-induced sarcomas showing similar rates of clear surgical margins but reduced survival outcomes in comparison to non radiation-induced head and neck sarcomas

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