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HIGH EXPRESSION OF MYOFERLIN IS ASSOCIATED WITH POOR OPSCC PATIENTS AND IS INVERSELY ASSOCIATED WITH HPV-STATUS

Oropharynx

Bhavna Kumar, MS¹, Nicole V Brown, MS², Benjamin J Swanson, MD, PhD³, Alessandra C Schmitt, MD³, Matthew Old, MD¹, Enver Ozer, MD¹, Amit Agrawal, MD¹, David E Schuller, MD¹, Theodoros N Teknos, MD¹, Pawan Kumar, MS, PhD¹

¹Department of Otolaryngology-Head and Neck Surgery, ²Center for Biostatistics, ³Department of Pathology, The Ohio State University, Columbus, OH

INCREASED RISK OF CERVICAL CANCER IN FEMALE SPOUSES OF OROPHARYNGEAL SQUAMOUS CELL CARCINOMA PATIENTS

Oropharynx

Marcus M Monroe, MD, Jason Hunt, MD, Luke Buchmann, MD, Lisa Cannon-Albright, PhD, Mia Hashibe, PhD

University of Utah School of Medicine

OUTCOME AND IMPACT OF HIGH-RISK HUMAN PAPILLOMAVIRUS IN PATIENTS TREATED WITH PRIMARY SURGERY FOR OROPHARYNGEAL CANCER

Oropharynx

Martina A Broglie, MD¹, Sandro J Stoeckli, MD¹, Philippe Pasche, MD², Antoine Reinhard, MD², Laurence de Leval, MD³, Gerhard F Huber, MD⁴, Thomas F Pezier⁴, Alex Soltermann, MD⁵, Roland Giger, MD⁶, Andreas Arnold, MD⁶, Eva Diamantis, MD⁷, Andre Arnoux, MD⁸, Martin Müller, MD⁸, Stephan Spreitzer, MD⁹, Florian Lang, MD¹⁰, Mathieu Lutchmaya, MD¹⁰, Edouard Stauffer, MD¹¹, Vittoria Espeli, MD¹², Francesco Martucci, MD¹³, Massimo Bongiovanni, MD¹⁴, Wolfram Jochum, MD¹⁵

¹Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital St.Gallen, Switzerland, ²Department of Otorhinolaryngology, Head and Neck Surgery, University of Lausanne, Switzerland, ³Department of Pathology, University hospital of Lausanne, Switzerland, ⁴Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Zurich, Switzerland, ⁵Institute of Surgical Pathology, University Hospital of Zurich, Switzerland, ⁶Department of Otorhinolaryngology, Head and Neck Surgery, University of Berne, Switzerland, ⁷Department of Pathology, University of Berne, Switzerland, ⁸Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Aarau, Switzerland, ⁹Department of Pathology, Kantonsspital Aarau, Switzerland, ¹⁰Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Fribourg, Switzerland, ¹¹Institute of Pathology, Promed SA, Fribourg, Switzerland, ¹²Oncology institute of southern Switzerland (IOSI) Bellinzona, Switzerland, ¹³Department of Radioonocolgy, Oncology institute of southern Switzerland (IOSI) Bellinzona, Switzerland, ¹⁴Institute of Pathology, Locarno, Switzerland, ¹⁵Institute of Pathology, Kantonsspital St. Gallen, Switzerland

SUPPRESSION OF ANTITUMOR IMMUNE RESPONSES BY HUMAN PAPILLOMAVIRUS THROUGH EPIGENETIC DOWNREGULATION OF CXCL14

Oropharynx

Louis Cicchini¹, Joseph Westrich¹, Daniel Vermeer², Jennifer Berger¹, Eric Clambey¹, Denis Lee¹, John Song¹, Paul Lambert¹, Robert Greer¹, John H Lee², Dohun Pyeon¹

¹University of Colorado, ²Sanford Health

NECK DOWNSTAGING AFTER 46 GY OF RADIOTHERAPY IS ASSOCIATED WITH HPV-RELATED OROPHARYNGEAL CARCINOMA.

Oropharynx

Emilie Dronkers, MD, Senada Koljenovic, MD, PhD, Gerda Verduijn, MD, Robert Baatenburg de Jong, MD, PhD, Jose Hardillo, MD, PhD

Erasmus University Medical Center Rotterdam

DIFFERENTIAL EXPRESSION OF ALDO-KETO-REDUCTASE 1C1 AND 1C3 GENES IS ASSOCIATED WITH VIRAL PHYSICAL STATUS IN HPV16 POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMAS

Oropharynx

Ernst Jan M Speel¹, Nadine C Olthof¹, Jutta Kolligs², Annick Haesevoets¹, Mieke Henfling¹, Frans C Ramaekers¹, Simon F Preuss², Dirk Beutner², Uta Drebber², Wan L Lam³, Emily A Vucic³, Bernd Kremer¹, Jens P Klussmann⁴, Christian U Huebbers²

¹Maastricht University Medical Center, ²University of Cologne, ³British Columbia Cancer Research Center, ⁴University Hospital of Giessen

18F-FDG PET/CT VERSUS HUMAN PAPILLOMAVIRUS, P16, AND EPSTEIN-BARR VIRUS DETECTION IN CERVICAL METASTATIC LYMPH NODES FOR IDENTIFYING PRIMARY TUMORS

Oropharynx

Gi Cheol Park, MD¹, Jong-Lyel Roh, MD, PhD², Kyung-Ja Cho, MD, PhD³, Jae Seung Kim, MD, PhD⁴, Seung-Ho Choi, MD, PhD², Soon Yuhl Nam, MD, PhD², Sang Yoon Kim, MD, PhD²

¹Department of Otolaryngology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea, ²Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, ³Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, ⁴Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

POSTOPERATIVE HEMORRHAGE IN PATIENTS TREATED BY TRANSORAL ROBOTIC SURGERY (TORS)

Oropharynx

Ashley Hay, MBChB, FRCS, MSc, Jocelyn Migliacci, MA, Daniella Karassawa Zanoni, MD, Jay O Boyle, MD, Bhuvanesh Singh, MD, PhD, Richard J Wong, MD, Snehal G Patel, MD, Ian Ganly, MD, PhD

Memorial Sloan Kettering Cancer Center

COMPLICATIONS FOLLOWING TRANSORAL ROBOTIC SURGERY (TORS): A DETAILED INSTITUTIONAL REVIEW OF COMPLICATIONS AND PREDICTIVE FACTORS.

Oropharynx

Ashley Hay, MBChB, FRCS, MSc, Jocelyn Migliacci, MA, Daniella Karassawa Zanoni, MD, Jay O Boyle, MD, Bhuvanesh Singh, MD, PhD, Richard J Wong, MD, Snehal G Patel, MD, Ian Ganly, MD, PhD

Memorial Sloan Kettering Cancer Center

TREATMENT OF P16 NEGATIVE RESECTABLE ADVANCED TONSILLAR CANCER, PRIMARY SURGERY OR PRIMARY RADIATION?

Oropharynx

Hui-Ching Chuang, MD, PhD, FACS¹, Chih-Yen Chien, MD, FACS¹, Fu-Min Fang, MD, PhD²

¹Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ²Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan