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RISK LEVEL STRATIFICATION USING CIRCULATING TUMOR DNA IN HEAD AND NECK CANCER PATIENTS

Cancer Biology

Liyona Kampel, MD, PhD; Sara Davidova, MD; Shlomo Zuriel, PhD; Narin Carmel Neiderman, MD; Dov Hershkovitz, MD, PhD; Nidal Muhanna, MD, PhD

Tel Aviv Sourasky Medical Center

EVEROLIMUS INHIBITS P53 MUTANT HNSCC BY MODULATING ANGIOGENESIS AND LYMPHANGIOGENESIS MECHANISMS LINKED TO MTOR/HIF1A/VEGF SIGNALING

Cancer Biology

Janmaris Marin Fermin; Md Maksudul Alam, PhD; Kyle A Boudreaux, MS, IV; Landon D Goodreau; Taylor L Powell; Tara Moore-Medlin; Xiaohua Rong; Jerry McLarty; Xin Gu; Cherie-Ann O Nathan

LSU-Health Shreveport

RADIATION IMPROVES THE THERAPEUTIC ANTIBODY DELIVERY IN HEAD AND NECK CANCERS.

Cancer Biology

Laura Freeman, MD; Guolan Lu, PhD; Eben Rosenthal

Stanford

CHARACTERIZING THE TUMOR MICROENVIRONMENT OF IMMUNOSUPPRESSED CUTANEOUS SQUAMOUS CELL CARCINOMA

Cancer Biology

Mica Glaun, MD¹; Frederico Gleber-Netto, PhD¹; Priyadharsini Nagarajan, MD¹; Tongxin Xie¹; Jennifer Covello¹; Shamima Akhter¹; Adebayo Adewale¹; Erez Baruch¹; Michael Wong¹; Kenneth Tsai²; Elsa Flores²; Michael Migden¹; Deborah Silverman¹; Ryan Goepfert¹; Yejing Ge¹; Padamanee Sharma¹; James Allison¹; Jeffrey Myers¹; Neil Gross¹; Moran Amit¹

¹MD Anderson Cancer Center; ²Moffitt Cancer Center

NEUTROPHIL TO LYMPHOCYTE RATIO AND PERIPHERAL BLOOD BIOMARKERS CORRELATE WITH OUTCOMES AMONG PATIENTS WITH RECURRENT METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA AND SALIVARY GLAND CANCER TREATED ON A PHASE II TRIAL OF PEMBROLIZUMAB AND VORINOSTAT

Immunotherapy / Systemic Therapy

Cassie Pan¹; Qian (Vicky) Wu²; Jenna Voutsinas²; Jeffrey J Houlton¹; Brittany Barber¹; Neal Futran¹; Renato G Martins³; Jonathan R Fromm⁴; Cristina P Rodriguez³

¹Department of Otolaryngology, University of Washington, Seattle, WA; ²Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA; ³Division of Oncology, Department of Medicine, University of Washington, Seattle, WA; ⁴Department of Laboratory Medicine, University of Washington, Seattle, WA

MASS SPECTROMETRY IMAGING OF THE METABOLIC LANDSCAPE OF HUMAN PAPILLOMAVIRUS-ASSOCIATED VERSUS CARCINOGEN-DRIVEN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Richard A Harbison, MD¹; William Andrews²; Rajeev Pandey¹; Rebecca Dempsey¹; Rajarsi Mandal¹; Robert Casero¹; Drew Pardoll¹; Carole Fakhry¹; Maureen Kane²; Jonathan Powell¹; Erika Pearce¹

¹Johns Hopkins Hospital; ²University of Maryland

5-AMINOLEVULINIC ACID FLUORESCENCE-GUIDED SURGERY IN HEAD AND NECK SQUAMOUS CELL CARCINOMA: A PILOT TRIAL

Cancer Engineering / Technology

Evan Kominsky; Brandon Gold; Annie Arrighi-Allisan; David Campbell; Mohemmed N Khan; Scott Roof; Constantinos Hadjipanayis; Eric Genden; Alfred Marc Iloreta

Icahn School of Medicine at Mount Sinai

PERIOPERATIVE TOPICAL ANTISEPSIS AND SURGICAL SITE INFECTION IN UPPER AERODIGESTIVE FREE FLAP RECONSTRUCTION

Reconstruction / Microvascular Surgery

Ahmed S Beydoun, MD¹; Andrew Holcomb, MD²; Priscilla Pichardo, DO³; Nicholas C Purdy, DO, FACS³; Chase M Heaton, MD⁴; Caitlin McMullen, MD⁵; Jessica A Yesensky, MD⁶; Michael Moore, MD⁶; Neerav Goyal, MD, MPH⁷; Joshua Kohan, BA⁸; Mirabelle Sajisevi, MD⁸; Kenneth Tan, BS⁹; Daniel Petrisor, MD, DDS⁹; Mark K Wax, MD, FACS, FRCS⁹; Zain Hassan, BS¹⁰; Skylar Trott, MD¹⁰; Andrew Larson, MD¹¹; Jeremy D Richmon, MD¹¹; Evan Graboyes, MD, MPH, FACS¹²; C B Wood, MD¹³; Ryan S Jackson, MD¹³; Patrik Pipkorn, MD¹³; Sid V Puram, MD, PhD¹³; Joseph Zenga, MD¹

¹Medical College of Wisconsin; ²Nebraska Methodist Health System; ³Geisinger Medical center; ⁴University of California, San Francisco; ⁵Moffitt Cancer Center; ⁶Indiana University School of Medicine; ⁷Penn State College of Medicine; ⁸University of Vermont Medical Center; ⁹Oregon Health & Science University; ¹⁰University of Kentucky; ¹¹Massachusetts Eye and Ear/Harvard Medical School; ¹²Medical University of South Carolina College of Medicine; ¹³Washington University School of Medicine

EFFECT OF PREOPERATIVE IMMUNOTHERAPY ON COMPLICATIONS AFTER HEAD AND NECK SURGERY

Immunotherapy / Systemic Therapy

Ramez Philips, MD; Angela Alnemri; Adam Luginbuhl, MD; David Cognetti, MD; Joseph Curry, MD

Thomas Jefferson University Hospitals

SUCCESS AND OUTCOMES FOLLOWING A SECOND SALVAGE ATTEMPT FOR FREE FLAP COMPROMISE: IS IT WORTHWHILE

Reconstruction / Microvascular Surgery

Allison A Slijepcevic, MD¹; Justin Shinn, MD²; Steve Cannady, MD²; Matthew M Hanasono, MD³; Matthew Old, MD⁴; Joseph M Curry, MD⁵; Jeewanjot Grewal, MD⁶; Tamer Ghanem, MD⁶; Yadro Ducic, MD⁷; Brett A Miles, MD⁸; Mark K Wax, MD¹

¹Oregon Health and Science University; ²University of Pennsylvania; ³MD Anderson; ⁴The Ohio State University; ⁵Thomas Jefferson University Hospitals; ⁶Henry Ford Hospital; ⁷Head and Neck Oncologic, Reconstructive, & Skull Base Surgery; ⁸Mount Sinai