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IMMUNE CHECKPOINT EXPRESSION ON TUMOR INFILTRATING LYMPHOCYTES (TIL) IS DEPENDENT ON HPV STATUS IN OROPHARYNGEAL CARCINOMA (OPSCC) - A SINGLE CELL RNA SEQUENCING ANALYSIS

Cancer Biology

A. von Witzleben¹; A. Grages¹; T. A. Kors¹; J. Thomas²; E. V. King³; J. Eziç¹; C. Brunner¹; P. J. Schuler¹; J. Kraus⁴; H. Kestler⁴; J. Doescher¹; C. Ottensmeier⁵; T. K. Hoffmann¹; S. Laban¹

¹Department of Otorhinolaryngology and Head & Neck Surgery, Ulm, Germany; ²Faculty of Medicine, Cancer Sciences Unit, Southampton, UK; ³Department of Otorhinolaryngology and Head & Neck Surgery, Poole Hospital, Poole, UK; ⁴Institute for Medical Systems Biology, Ulm, Germany; ⁵Department of Molecular & Clinical Cancer Medicine, University of Liverpool, UK

THE GENETIC LANDSCAPE OF HEAD AND NECK CANCER USING BRUSH BIOPSY

Cancer Biology

Evit John, BDS, MPH, PhD, Candidate¹; Xiao Zhao, MD, PHD¹; Peter Van Loo, PHD¹; Tom Lesluyes, PHD²; Toby Baker, PhD Candidate²

¹MD Anderson Cancer Center; ²The Francis Crick Institute

AUTOMATED MACHINE LEARNING-BASED CLASSIFICATION CORRESPONDS TO PATHOLOGIST CLASSIFICATION OF HEAD AND NECK CANCER PATIENT DERIVED ORGANOID MORPHOLOGY

Cancer Biology

Anuraag S Parikh, MD¹; Andres Klein-Szanto, MD, PhD²; Daria Vasilyeva, DDS¹; Ogoegbunam Okolo, BS¹; Victoria X Yu, MD¹; Samuel P Flashner, PhD¹; Cecilia Martin, BS¹; Masataka Shimonosono, PhD¹; Salvatore M Caruana, MD¹; Scott H Troob, MD¹; Angela J Yoon, DDS³; Devraj Basu, MD, PhD⁴; Fatemeh Momen-Heravi, DDS, PhD¹; Hiroshi Nakagawa, MD, PhD¹

¹Columbia University; ²Fox Chase Cancer Center; ³Medical University of South Carolina; ⁴University of Pennsylvania

EFFECT OF EPHEDRA SINICA EXTRACT ON THE SENSITIVITY OF RADIOTHERAPY IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Young-Gyu Eun; Hee Jin Kang; Su Il Kim; Young Chan Lee

Kyung Hee University

DIFFERENTIAL EXPRESSION OF MMP-2 AND MMP-9 ON ORAL SQUAMOUS CELL CARCINOMA (OSCC) SUBSITES AND THEIR CLINICAL SIGNIFICANCE

Cancer Biology

S. Lynn Sigurdson, PhD; Subin Surendran, PhD; William J Magner, PhD; Moni A Kuriakose, MD; Wesley L Hicks, Jr., DDS, MD

Roswell Park Comprehensive Cancer Center, Buffalo NY

EFFICACY OF DEPATUXIZUMAB MAFODTIN (ABT-414) IN EGFR-EXPRESSING HEAD AND NECK CANCER

Cancer Biology

Lucas D Mani¹; Guolan Lu, PhD²; Marisa Hom, PhD¹; Abdullah Naveed, MD¹; Eben Rosenthal, MD¹

¹Vanderbilt University Medical Center; ²Stanford University

EXPLORING THE ROLE OF SENESCENCE IN ORAL CARCINOGENESIS

Cancer Biology

Jessica Bourbonnais, MSc¹; Francis Rodier, PhD¹; Apostolos Christopoulos, MD, MSc²

¹Institut du Cancer de Montréal, CRCHUM; ²CHUM

5-AZACYTIDINE PROMOTES IMMUNE RECOGNITION AND T CELL INFILTRATION IN HPV-POSITIVE HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENTS

Cancer Biology

Jason Tasoulas, MD, DMD¹; Andrew Sewell, MD, PhD¹; Hina Rehmani, PhD¹; David Rimm, MD, PhD²; Karen S Anderson, PhD²; Barbara Burtness, MD²; Wendell G Yarbrough, MD, MMHC, FACS¹; Natalia Issaeva, PhD¹

¹University of North Carolina at Chapel Hill; ²Yale University

PROGNOSTIC FACTORS IN OLIGOMETASTATIC DISEASE: A PAN-CANCER SYSTEMATIC REVIEW AND META-ANALYSIS

Cancer Biology

Yiu Tsun Kwan, MBBS; Chong Boon Teo, MBBS; Kai Xun Joshua Tay, MBBS, PHD

NUHS

THE IMPLICATIONS OF MICROBIOME DIFFERENCES IN HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC)

Cancer Biology

Tomasz Zatonski, Prof

Wroclaw Medical University, ENT H&N Surgery Dep.