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MTOR INHIBITOR INDUCES AUTOPHAGY AND REDUCES TUMOR VASCULARIZATION TO PREVENT TUMOR GROWTH OF TP53 MUTANT HNSCC

Cancer Biology

Maksudal Alam, MD PhD; Janmaris Marin Fermin, MD; Chaning Dorr, BS; Hillary Savage, BFA; Patrick Spiller, MD; Xiaohua Rong; Tara Moore-Medlin, BS; Caden O Maxwell; Alok R Khandelwal, PhD; Cherie-Ann O Nathan, MD, FACS

Department of Otolaryngology-Head and Neck Surgery, LSU Health-Shreveport, Shreveport, Louisiana, USA.

MIXED EXTRAGONADAL GERM CELL TUMOR OF THE ADULT LATERAL NECK

Cancer Biology

1; Khaled Campa, MD²; Mohamedkazim Alwani, MD¹; Sarah Drejet, MD³; Chad Galer, MD¹

¹Indiana University Department of Otolaryngology – Head and Neck Surgery; ²University of Colorado Department of Otolaryngology - Head and Neck Surgery; ³University of Utah Department of Otolaryngology - Head and Neck Surgery

ATAD3A CONFERS MALIGNANT POTENTIAL IN HEAD AND NECK CANCER VIA ITS ATP-BINDING ABILITY

Cancer Biology

1; Tiffany Lam¹; Alex Chen¹; Reid Loveless¹; Chloe Shay²; Yong Teng¹

¹Ausugusta University; ²Emory University

DETECTION OF HPV IN SQUAMOUS CELL CARCINOMA IN HEAD AND NECK, OUR FIRST CASES, JANUARY 2014 –OCTOBER 2020. SALUD INTEGRAL HOSPITAL, MANAGUA, NICARAGUA .

Cancer Biology

Francisco Medrano, Head Neck Surgeon¹; Carmen Quezada, Pathologist¹; Guillermo Carmona, Surgeon¹; Roger Matus, Radiologist²; Roger Padilla, Facial Maxilo Surgeon¹

¹Salud Integral Hospital; ²X Ray Center

BETA SPECTRIN STAINING IS ASSOCIATED WITH HIGHER RISK OF RECURRENT DISEASE IN ORAL TONGUE SQUAMOUS CELL CARCINOMA (OTSCC)

Cancer Biology

Isabel Randolph; William Adams, PhD; Swati Mehrotra, MD; Mitchell Denning, PhD; Carol Bier-Laning, MD, MBA, FACS

Loyola University Medical Center

TMEM16A MAY SERVE AS A BIOMARKER FOR TARGETING P90RSK MEDIATED CISPLATIN RESISTANCE

Cancer Biology

Nayel Khan¹; Suman Chatterjee¹; Eric Huang²; Avani Vyas¹; Wangjie Yu²; Silvia Cruz-Rangel¹; Vlad Sandulache²; Timothy Burns³; Umamaheswar Duvvuri¹

¹Dept of Otolaryngology, UPMC; ²Bobby R. Alford Department of Otolaryngology, BCM; ³Dept of Medicine, Division of Hematology/Oncology, UPCI

CHARACTERIZATION OF THE TRANSCRIPTOME OF THE ADENOID CYSTIC CARCINOMA PATIENT- DERIVED XENOGRAFT

Cancer Biology

James Cevallos, BS¹; Philippe Boileau, BS²; Joseph Humtsoe, PhD³; Leilani Jones, BS³; Patrick Ha, MD³

¹UCSF School of Medicine; ²UCB Graduate Group in Biostatistics; ³UCSF Department of Otolaryngology, Head and Neck Surgery

POTENTIAL OF T-DM1 (KADCYLA) FOR TREATMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Jacqueline Pei, BS; Yu-Jin Lee, MD; Nynke van den Berg, PhD; Marisa Hom, PhD; Brock A Martin, MD; Eben L Rosenthal, MD

Stanford University

EVALUATION OF THE IMMUNE LANDSCAPE BY DIGITAL CYTOMETRY USING TRANSCRIPTOMIC DATA OF ORAL PRE-MALIGNANT LESIONS

Cancer Biology

Vaishnav Vasudevan¹; Hari P S²; Sumsum P Sunny³; Vijay Pillai³; Vivek Shetty³; Vidya Bhushan³; Narayana Subramaniam³; Nameeta Shah²; Moni A Kuriakose³; Amritha Suresh¹

¹Integrated Head and Neck Oncology Research Program, Mazumdar Shaw Medical Foundation, Narayana Health, Bengaluru, India; ²Neuro-Oncology Program, Mazumdar Shaw Medical Foundation, Narayana Health, Bengaluru, India; ³Head and Neck Oncology, Mazumdar Shaw Medical Center, Narayana Health, Bengaluru, India

FOXP3+ REGULATORY T CELLS ACCUMULATE DURING ORAL CAVITY SQUAMOUS CELL CANCER PROGRESSION

Cancer Biology

1; Andrew Tu, MS¹; Usama Aboelkheir, MD¹; William J Magner, PhD¹; S. Lynn Sigurdson, PhD¹; Michael R Markiewicz, MD, DDS, MPH¹; Wesley L Hicks, Jr, DDS, MD¹; Amritha Suresh, PhD²; Mihai Merzianu, MD¹; Kimberly Wooten, MD¹; Moni A Kuriakose²

¹Roswell Park Comprehensive Cancer Center; ²Mazumdar Shaw Medical Center- Roswell Park Collaboration Program