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Poster Abstracts

P021

PATTERNS OF DISTANT METASTASIS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA AND THEIR PROGNOSTIC SIGNIFICANCE

Cancer Biology

Diako Berzenji; Aniel Sewnaik; Stijn Keereweer; Dominiek Monserez; Gerda Verduijn; Esther van Meerten; Hetty Mast; Marc Mureau; Aad van der Lugt; Senada Koljenovic; Robert Jan Baatenburg de Jong; Jose Hardillo

Erasmus MC Cancer Institute


P022

ANALYSIS OF THE SYNERGETIC EFFECT OF AUTOPHAGY INHIBITOR CHLOROQUINE IN COMBINATION WITH CETUXIMAB OR CISPLATIN IN HEAD AND NECK SQUAMOUS CELL CARCINOMA CELL LINES

Cancer Biology

M Bernard; GC Cardin; M Cahuzac; J Bourbonnais; H Bahig; PF Nguyen-Tan; O Ballivy; E Filion; D Soulieres; T Ayad; L Guertin; E Bissada; A Christopoulos

CRCHUM


P023

TRANSCRIPTOMIC ANALYSES OF OBESITY-DRIVEN ORAL CANCER PROGRESSION

Cancer Biology

1; Lixia Zhang, MD, MS1; Zhenning Li, DDS, MD1; Jonathan E Bard, MS1; Jon M Chan, MD2; Keith L Kirkwood, DDS, PhD1

1Univeristy at Buffalo; 2Roswell Park Comprehensive Cancer Center


P025

DEPENDENCE OF CELL CYCLE CHECKPOINT PROTEINS IN HPV+ AND HPV- HEAD AND NECK SQUAMOUS CELL CARCINOMA CELLS FOLLOWING 4NQO-INDUCED DNA DAMAGE

Cancer Biology

Gauri Shishodia; Rhodie R Toledo; Emily Zimmerman; Xiaohua Rong; Adam Xiao; Lynn Harrison; Cherie A Nathan

LSU Health Sciences Center


P026

APOBEC MUTAGENESIS IS CONCORDANT BETWEEN TUMOR AND VIRAL GENOMES IN HPV POSITIVE HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Daniel L Faden1; Maoxuan Lin1; Krystle A Lang Kuhs2; Jim Lewis3; Micheal Lawrence4; Lisa Mirabello5; Robert L Ferris6

1Mass. Eye and Ear, Harvard Medical School; 2University of Kentucky; 3Vanderbilt Medical Center; 4Mass. General Hospital, Harvard Medical School; 5NCI/NIH; 6University of Pittsburgh Medical Center


P027

CORRELATION OF ALTERATIONS IN THE KEAP1/CUL3/NFE2L2 PATHWAY WITH RADIATION FAILURE IN LARYNGEAL SQUAMOUS CELL CARCINOMA

Cancer Biology

Douglas A Farquhar; Siddharth Sheth, MD, MPH; Wendell G Yarbrough, MD; Trevor Hackman, MD; Adam Zanation, MD

University of North Carolina


P028

THE IMPACT OF HISTOPATHOLOGIC FEATURES ON CACHEXIA SEVERITY IN HEAD & NECK CANCER PATIENTS

Cancer Biology

Alexander J Jones, MD; Leah J Novinger, MD, PhD; Marelle R Ruke, BS; Andrea Bonetto, PhD; Kyle P Davis, BS; Michael G Moore, MD, FACS; Jessica A Yesensky, MD

Indiana University School of Medicine


P029

POTENTIAL USE OF EXOSOMES IN IMMUNOTHERAPY FOR PLATINUM REFRACTORY ORAL CAVITY CANCER

Cancer Biology

Subin Surendran, PhD1; S. Lynn Sigurdson, PhD1; William J Magner, PhD1; Amritha Suresh, PhD2; Keith L Kirkwood, DDS, PhD3; Michael R Markiewicz, MD, DDS, MPH1; Jon Chan, MD1; Anurag Singh, MD1; Moni A Kuriakose, MD1

1Roswell Park Comprehensive Cancer Center; 2Mazumdar Shaw Medical Center- Roswell Park Collaboration Program; 3University at Buffalo School of Dental Medicine


P030

ORAL MICROBIOME COMMUNITY COMPOSITION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA: A CASE-CONTROL STUDY

Cancer Biology

William J Benjamin, MPH1; Kai Wang, PhD2; Katie Zarins, MPH1; Emily Bellile, MS3; Jeremy M G Taylor, PhD3; Samara Rifkin, MD4; Maureen Sartor2; Laura S Rozek1

1Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA; 2Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA; 3Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA; 4Department of Gastroenterology, University of Michigan, Ann Arbor, MI, USA


P031

INCREASED TUMOR EXOSOME PRODUCTION MAY CONTRIBUTE TO ORAL CAVITY IMMUNE EVASION

Cancer Biology

1; Andrew Tu, MS1; William J Magner, PhD1; S. Lynn Sigurdson, PhD1; Michael R Markiewicz, MD, DDS, MPH1; Mihai Merzianu, MD1; Vishal Gupta, MD1; Kimberly Wooten, MD1; Jon Chan, MD1; Amritha Suresh, PhD2; Moni A Kuriakose, MD2

1Roswell Park Comprehensive Cancer Center; 2Mazumdar Shaw Medical Center- Roswell Park Collaboration Program