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Poster Abstracts

P032

MARCH6 PROMOTES PAPILLARY THYROID CANCER DEVELOPMENT BY DESTABILIZING DHX9

Cancer Biology

Yang Liu, MD; Siyuan Xu; Ying Huang, MD; Shaoyan Liu; Zhengang Xu; Jie Liu, MD

Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College


P033

THE RS6942067 GG GENOTYPE IS ASSOCIATED WITH A WORSE OVERALL SURVIVAL IN HEAD AND NECK SQUAMOUS CELL CARCINOMA AND WITH N+ PATIENTS EITHER UNDER 42 YEARS OLD OR NON-SMOKING HPV NEGATIVE

Cancer Biology

Guillaume B. Cardin1; Monique Bernard1; Houda Bahig2; Felix-Phuc Nguyen-Tan2; Edith Filion2; Denis Soulieres2; Danielle Charpentier2; Olguta Gologan2; Tareck Ayad2; Louis Guertin2; Eric Bissada2; Jean-Claude Tabet2; Francis Rodier1; Apostolos Christopoulos2

1Centre de Recherche du Centre Hospitalier de l'Université de Montréal; 2Centre hospitalier de l'Université de Montréal


P034

THE SPECTRUM OF TUMOR MUTATIONAL BURDEN IN A HEAD AND NECK CANCER COHORT

Cancer Biology

1; Jacob Friedman, MD1; Michael Jelinek, MD2; Mary Jo Fidler, MD2; Nikhil Joshi, MD3; Kerstin Stenson, MD1; Mihir Bhayani, MD1; Samer Al-Khudari1

1Department of Otorhinolaryngology - Head and Neck Surgery, Rush University Medical Center; 2Department of Internal Medicine - Medical Oncology, Rush University Medical Center; 3Department of Radiation Oncology, Rush University Medical Center


P035

EFFECT OF OPIOID RECEPTOR ACTIVATION AND BLOCKAGE ON THE PROGRESSION AND RESPONSE TO TREATMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Lirit Levi, MD1; Hagit Shoffel-Havakuk, MD1; Elad Hikri, MD, PHD2; Avraham Dayan2; Aron Popovtzer3; Gideon Bachar1; Aviram Mizrachi1

1Department of Otorhinolaryngology - Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Institute of Oncology, Hadassah Medical Center and the Hebrew University, Jerusalem, Israel


P036


P037

IDO1 AND CXCL11 MRNA GENE EXPRESSIONS, ADJUSTED FOR TP53 GENOMIC ABERRATIONS AND PD1/PDL1 MRNA GENE EXPRESSIONS, ARE PROGNOSTIC IN PATIENTS WITH STAGE III-IVB HPV-NEGATIVE HNSCC

Cancer Biology

Evan M De Joya, BS; Stuart E Samuels, MD, PhD; Gregory A Azzam, MD, PhD; Laura M Freedman, MD; Susan H Blanton, PhD; Cesar A Perez, MD; Zoukaa B Sargi, MD, MPH; Michael Samuels, MD; Ruben Carmona, MD, MAS

University of Miami, Miller School of Medicine


P038

NY-ESO-1 EXPRESSION IN ORAL PRE-MALIGNANT AND MALIGNANT LESIONS

Cancer Biology

William J Magner, PhD1; Subin Surendran, PhD1; Vishal Gupta, MD1; Kimberly Wooten, MD1; Ryan P McSpadden, MD1; Jon Chan, MD1; S. Lynn Sigurdson, PhD1; Mihai Merzianu, MD1; Wesley L Hicks Jr, DDS, MD1; Adekunle O Odunsi, MD, PhD1; Moni A Kuriakose2; Amritha Suresh, PhD2

1Roswell Park Comprehensive Cancer Center; 2Mazumdar Shaw Medical Center-Roswell Park Collaboration Program, Bangalore India


P039

ACTIN-ASSOCIATED GENE EXPRESSION IS ASSOCIATED WITH EARLY REGIONAL METASTASIS OF TONGUE CANCER.

Cancer Biology

Young Kang, MD1; Doh Young Lee, MD2; Dong Wook Lee, MD, PhD1

1Department of Otorhinolaryngology Head and Neck Surgery, Chungbuk National University College of Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea; 2Department of Otorhinolaryngology Head and Neck Surgery, Seoul Nation University Boramae Medical Center, Seoul, South Korea


P040

NOVEL ANAPLASTIC THYROID CANCER PATIENT-DERIVED XENOGRAFT MODELS AND CELL LINES: EXPANDING THE MOLECULAR DIVERSITY OF IN VITRO AND IN VIVO MODELS

Cancer Biology

Anastasios Maniakas, MD, MSc1; Ying C Henderson, MD, PhD2; Hu Hei, MD2; Shaohua Peng, PhD2; Yunyun Chen, PhD2; Yujie Jiang, BS2; Shuangxi Ji, PhD2; Maria Cardenas, BA3; Yulun Chiu, PhD2; Diana Bell, MD2; Michelle D Williams, MD2; Marie-Claude Hofmann, PhD2; Steve E Scherer, PhD3; David A Wheeler, PhD3; Naifa L Busaidy, MD2; Ramona Dadu, MD2; Jennifer R Wang, MD, MSc2; Maria E Cabanillas, MD2; Mark Zafereo, MD2; Faye M Johnson, MD, PhD2; Stephen Y Lai, MD, PhD2

1Université de Montréal - Hôpital Maisonneuve-Rosemont; MD Anderson Cancer Center; 2MD Anderson Cancer Center; 3Baylor College of Medicine


P041

NOVEL MEDIATORS OF THE P63-DRIVEN ONCOGENIC PROCESSES IN SQUAMOUS CELL CARCINOMA

Cancer Biology

Alexandra Glathar; Akinsola Oyelakin; Christian Gluck, MD, PhD; Satrajit Sinha, PhD

University at Buffalo