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Poster Abstracts

P042

FEASIBILITY OF SALIVA TESTING USING METHYLATED MICRORNAS FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA RECURRENCE

Cancer Biology

1; Wafik Sedhom, MD1; Derek Smith1; Francis Hall, MD1; Vivian Wu, MD1; Ling Lu, PhD1; Elyse Handley1; Dexiang Gao, PhD1; Sophia Bornstein, MD, PhD2; Neil Gross, MD3; Brian Harry, MD, PhD1; Jose Zevallos, MD4; John Song, MD1; Shi-Long Lu, MD, PhD1

1University of Colorado; 2Oregon Health and Science University; 3MD Anderson Cancer Center; 4Washington University


P043

ROLE OF AXL AND EPITHELIAL-MESENCHYMAL TRANSITION IN CLASSIC AND MIXED VARIANTS OF ANAPLASTIC THYROID CANCER

Cancer Biology

1; Rebecca R Pharaon, BA2; Kimberley-Jane C Bonjoc, BS2; Feras Ally, MD2; Holly Yin, PhD2; Robert Kang, MD2; Thomas Gernon, MD2; Ellie Maghami, MD2; Ammar Chaudhry, MD2

1University of Utah; 2City of Hope National Medical Center


P044

TARGETING TUMOR METABOLISM THROUGH LACTATE DEHYDROGENASE A INHIBITS TUMOR PROGRESSION IN ANAPLASTIC THYROID CANCER XENOGRAFTS

Cancer Biology

Yunyun Chen, PhD1; Meng Cui, MD, PhD1; Xiangdong Le, MS1; Joshua S Niedzielski, PhD2; Anastasios Maniakas, MD, MSc1; Ying C Henderson, MD, PhD1; Jim Bankson, PhD2; Vlad Sandulache, MD, PhD3; Stephen Y Lai, MD, PhD1

1Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 3Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA


P045

SUBSITE SPECIFIC PROTEOMIC ANALYSIS OF ORAL SQUAMOUS CELL CARCINOMA TO IMPROVE TREATMENT AND OUTCOMES

Cancer Biology

Subin Surendran, PhD1; William J Magner, PhD1; S. Lynn Sigurdson, PhD1; Vishal Gupta, MD1; Wesley L Hicks, Jr, DDS, MD1; Keith L Kirkwood, DDS, PhD2; Amritha Suresh, PhD3; Moni A Kuriakose, MD3

1Roswell Park Comprehensive Cancer Center; 2University at Buffalo School of Dental Medicine; 3Mazumdar Shaw Medical Center- Roswell Park Collaboration Program


P047

EVALUATION OF APOPTOSIS SIGNALING IN HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) DEMONSTRATES DEPENDENCE ON BCL-FAMILY PRO-SURVIVAL MOLECULES

Cancer Biology

Daniel Li1; Andrea Lopez, PhD2; Denis Reyna, PhD2; Carlos Thomas1; Nitisha Shrivastava, PhD1; Cory Fulcher, MD3; Michael B Prystowsky, MD, PhD1; Evripidis Gavathiotis, PhD2; Thomas J Ow, MD, MS3

1Albert Einstein College of Medicine, Department of Pathology; 2Albert Einstein College of Medicine, Department of Biochemistry; 3Montefiore Medical Center, Department of Otorhinolaryngology-Head and Neck Surgery


P048

OVEREXPRESSION OF ENO1 PROMOTES THYROID CANCER GROWTH BY REGULATING CYSTATIN 1 AND CYSTATIN 4

Cancer Biology

Yang Liu; Jie Liu; Shaoyan Liu

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical, Sciences and Peking Union Medical College


P049

UNCOVERING ANATOMICAL SUBSITE SPECIFIC TRANSCRIPTIONAL NETWORKS IN ORAL CAVITY SQUAMOUS CELL CARCINOMA

Cancer Biology

Christian Gluck, PhD1; Michael R Markiewicz, MD, DDS, MPH1; Amritha Suresh, PhD2; Moni A Kuriakose, MD2; William J Magner, PhD1; Lynn Sigurdson1; Ryan P McSpadden, MD1; Anurag K Singh, MD1; Satrajit Sinha, PhD3; Wesley L Hicks, Jr, DDS, MD1

1Roswell Park Comprehensive Cancer Center; 2Mazumdar Shaw Medical Center- Roswell Park Collaboration Program; 3University at Buffalo


P050

METHYLATION AND GENE EXPRESSION DIFFERENCES BETWEEN ASC/TMS1 AND MYD88 GENES IN HEALTHY AND CANCER LARYNGEAL TISSUE

Cancer Biology

Mario Bilic1; Lana Kovac Bilic1; Jelena Knezevic2; Maja Sutic2

1University Hospital Center Zagreb, Croatia; 2Ruder Boskovic Institute Zagreb, Croatia


P052

ACETYL ISOGAMBOGIC ACID INDUCES ER STRESS AND CELL DEATH IN ORAL CAVITY CANCER CELLS

Cancer Biology

Thomas Jetmore, MD; William Mason; Andrew Fribley

Wayne State University


P053

EXTENSIVE RESECTION OF NEWLY REPLICATED DNA IN IRRADIATED HPV-POSITIVE HNSCC CELL LINES

Cancer Biology

Christian S Betz; Janine Burmester; Malte Kriegs; Sabrina Christiansen; Kai Rothkamm; Thorsten Rieckmann

University Medical Center Hamburg-Eppendorf