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DYSREGULATED EXPRESSION OF HPV RELATED LNCRNA PTENP1 BY SMOKING INDUCES CANCER DRUG RESISTANCE AND RECURRENCE THROUGH C-MYC ACTIVATION

Cancer Biology

Zixing Liu; Jose Zevallos

Washington University in St Louis, School of Medcine

IN VITRO AND IN VIVO EFFICACY OF ANTIBODY-DRUG CONJUGATE TARGETING HER2 IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Yu-Jin Lee, MD¹; Jacqueline Pei²; Estelle Martin¹; Quan Zhou, PhD¹; Marisa Hom, PhD³; Laura Freeman, MD¹; Guolan Lu¹; Eben Rosenthal, MD³

¹Stanford University; ²University of Miami; ³Vanderbilt University

CHARACTERIZATION OF HUMAN PAPILLOMAVIRUS IN SINONASAL SQUAMOUS CELL CARCINOMA

Cancer Biology

Elisabeth E Hansen, MSc¹; Michael Lawrence, PhD²; Lisa Mirabello, PhD³; James S Lewis, MD⁴; Daniel L Faden, MD¹

¹Mass. Eye and Ear, Harvard Medical School; ²Mass. General Hospital, Harvard Medical School; ³NCI/NIH; ⁴Vanderbilt Medical Center

THE TUMOR IMMUNE LANDSCAPE OF HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Chareeni Kurukulasuriya, BS¹; Honesty Kim, PhD²; Alex Trevino, PhD²; Blaize D'Anglo²; Ryan Preska²; Aaron Mayer, PhD²; Umamaheswar Duvvuri, MD, PhD³

¹University of Pittsburgh School of Medicine; ²Enable Medicine; ³University of Pittsburgh Medical Center

CISPLATIN RESISTANCE IN HEAD AND NECK CANCER: IMPACT OF SECONDHAND SMOKE EXPOSURE

Cancer Biology

Balaji Sadhasivam, PhD¹; Jimmy Manyanga, PhD²; Vengatesh Ganapathy, PhD²; Célia Bouharati, BS²; Toral Mehta, PhD²; Basil Mathews, MD²; Samuel Castles, MD²; David Rubenstein, PhD³; Alayna Tackett, PhD⁴; Pawan Acharya, MS⁵; Daniel Zhao, PhD⁶; Lurdes Queimado, MD, PhD⁷

¹Departments of Otolaryngology Head and Neck Surgery, The University of Oklahoma Health Sciences Center; ²Departments of Otolaryngology Head and Neck Surgery and Cell Biology, The University of Oklahoma Health Sciences Center; ³Department of Biomedical Engineering, Stony Brook University, New York; ⁴Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California Los Angeles; ⁵Department of Biostatistics, The University of Oklahoma Health Sciences Center; ⁶Department of Biostatistics and TSET Health Promotion Research Center, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center; ⁷Departments of Otolaryngology Head and Neck Surgery, Cell Biology, and TSET Health Promotion Research Center, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center

RISK LEVEL STRATIFICATION USING CIRCULATING TUMOR DNA IN HEAD AND NECK CANCER PATIENTS

Cancer Biology

Liyona Kampel, MD, PhD; Sara Davidova, MD; Shlomo Zuriel, PhD; Narin Carmel Neiderman, MD; Dov Hershkovitz, MD, PhD; Nidal Muhanna, MD, PhD

Tel Aviv Sourasky Medical Center

EVEROLIMUS INHIBITS P53 MUTANT HNSCC BY MODULATING ANGIOGENESIS AND LYMPHANGIOGENESIS MECHANISMS LINKED TO MTOR/HIF1A/VEGF SIGNALING

Cancer Biology

Janmaris Marin Fermin; Md Maksudul Alam, PhD; Kyle A Boudreaux, MS, IV; Landon D Goodreau; Taylor L Powell; Tara Moore-Medlin; Xiaohua Rong; Jerry McLarty; Xin Gu; Cherie-Ann O Nathan

LSU-Health Shreveport

RADIATION IMPROVES THE THERAPEUTIC ANTIBODY DELIVERY IN HEAD AND NECK CANCERS.

Cancer Biology

Laura Freeman, MD; Guolan Lu, PhD; Eben Rosenthal

Stanford

CHARACTERIZING THE TUMOR MICROENVIRONMENT OF IMMUNOSUPPRESSED CUTANEOUS SQUAMOUS CELL CARCINOMA

Cancer Biology

Mica Glaun, MD¹; Frederico Gleber-Netto, PhD¹; Priyadharsini Nagarajan, MD¹; Tongxin Xie¹; Jennifer Covello¹; Shamima Akhter¹; Adebayo Adewale¹; Erez Baruch¹; Michael Wong¹; Kenneth Tsai²; Elsa Flores²; Michael Migden¹; Deborah Silverman¹; Ryan Goepfert¹; Yejing Ge¹; Padamanee Sharma¹; James Allison¹; Jeffrey Myers¹; Neil Gross¹; Moran Amit¹

¹MD Anderson Cancer Center; ²Moffitt Cancer Center

MASS SPECTROMETRY IMAGING OF THE METABOLIC LANDSCAPE OF HUMAN PAPILLOMAVIRUS-ASSOCIATED VERSUS CARCINOGEN-DRIVEN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Cancer Biology

Richard A Harbison, MD¹; William Andrews²; Rajeev Pandey¹; Rebecca Dempsey¹; Rajarsi Mandal¹; Robert Casero¹; Drew Pardoll¹; Carole Fakhry¹; Maureen Kane²; Jonathan Powell¹; Erika Pearce¹

¹Johns Hopkins Hospital; ²University of Maryland