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CRISPR-MEDIATED EPIGENETIC EDITING IDENTIFIES GENE REPRESSION PATTERNS IN HPV+ HEAD AND NECK CANCER AND MODULATES CELL GROWTH

Cancer Biology

Andrey Finegersh; Koji Ebisumoto; Sayed Sadat; Joseph Califano

UCSD

12-MONTH SMOKING CESSATION PROGRAM LOWERS SOLUBLE CD44 LEVELS IN A HIGH-RISK POPULATION

Cancer Biology

Drew H Smith, MD, MS¹; Shahm Raslan²; Isildinha M Reis, PhD¹; Huaping Liu¹; Jerri Halgowich¹; Claudia Gordon¹; Elizabeth J Franzmann, MD¹

¹University of Miami Leonard Miller School of Medicine; ²Florida International University Herbert Wertheim College of Medicine

EXOSOMES FROM PRIMARY TUMOR CULTURED FROM HPV+ AND HPV- OROPHARYNGEAL CANCER DEMONSTRATE DIFFERENTIAL EXPRESSION OF MIR INVOLVED IN EMT

Cancer Biology

Vivian F Wu, MD, MPH; David Dai, PhD

HFHS

THERAPEUTIC TARGETING OF GLUTAMINOLYSIS AND MITOCHONDRIAL TCA CYCLE IN HEAD AND NECK CANCER

Cancer Biology

Yong Teng¹; LW Lang²; R Loveless²; LL He²; Chloe Shay¹

¹Emory University; ²Augusta University

EXTENSIVE RESECTION OF NEWLY REPLICATED DNA IN IRRADIATED HPV-POSITIVE HNSCC CELL LINES

Cancer Biology

Christian S Betz; Janine Burmester; Malte Kriegs; Sabrina Christiansen; Kai Rothkamm; Thorsten Rieckmann

University Medical Center Hamburg-Eppendorf

ACETYL ISOGAMBOGIC ACID INDUCES ER STRESS AND CELL DEATH IN ORAL CAVITY CANCER CELLS

Cancer Biology

Yue Xi, PhD; Chester Gauss; Mehrnoosh Ghafouri AbbasAbadi; Thomas Jetmore, MD; William Mason; Andrew Fribley

Wayne State University

METHYLATION AND GENE EXPRESSION DIFFERENCES BETWEEN ASC/TMS1 AND MYD88 GENES IN HEALTHY AND CANCER LARYNGEAL TISSUE

Cancer Biology

Mario Bilic¹; Lana Kovac Bilic¹; Jelena Knezevic²; Maja Sutic²

¹University Hospital Center Zagreb, Croatia; ²Ruder Boskovic Institute Zagreb, Croatia

UNCOVERING ANATOMICAL SUBSITE SPECIFIC TRANSCRIPTIONAL NETWORKS IN ORAL CAVITY SQUAMOUS CELL CARCINOMA

Cancer Biology

Christian Gluck, PhD¹; Michael R Markiewicz, MD, DDS, MPH¹; Amritha Suresh, PhD²; Moni A Kuriakose, MD²; William J Magner, PhD¹; Lynn Sigurdson¹; Ryan P McSpadden, MD¹; Anurag K Singh, MD¹; Satrajit Sinha, PhD³; Wesley L Hicks, Jr, DDS, MD¹

¹Roswell Park Comprehensive Cancer Center; ²Mazumdar Shaw Medical Center- Roswell Park Collaboration Program; ³University at Buffalo

OVEREXPRESSION OF ENO1 PROMOTES THYROID CANCER GROWTH BY REGULATING CYSTATIN 1 AND CYSTATIN 4

Cancer Biology

Yang Liu; Jie Liu; Shaoyan Liu

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical, Sciences and Peking Union Medical College

EVALUATION OF APOPTOSIS SIGNALING IN HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) DEMONSTRATES DEPENDENCE ON BCL-FAMILY PRO-SURVIVAL MOLECULES

Cancer Biology

Daniel Li¹; Andrea Lopez, PhD²; Denis Reyna, PhD²; Carlos Thomas¹; Nitisha Shrivastava, PhD¹; Cory Fulcher, MD³; Michael B Prystowsky, MD, PhD¹; Evripidis Gavathiotis, PhD²; Thomas J Ow, MD, MS³

¹Albert Einstein College of Medicine, Department of Pathology; ²Albert Einstein College of Medicine, Department of Biochemistry; ³Montefiore Medical Center, Department of Otorhinolaryngology-Head and Neck Surgery